Symbol Name ID |
Rubcn
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein MGI:1915160 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Mouse Phenotypes | immune system phenotype |
increased neutrophil cell number |
increased CD8-positive, alpha-beta T cell number |
increased lymphocyte cell number |
increased monocyte cell number |
abnormal spleen morphology |
increased IgG level |
abnormal macrophage physiology |
abnormal circulating chemokine level |
increased circulating interleukin-1 beta level |
decreased circulating interleukin-10 level |
increased circulating interleukin-12b level |
increased circulating interleukin-6 level |
increased susceptibility to systemic lupus erythematosus |
increased autoantibody level |
increased anti-nuclear antigen antibody level |
increased anti-double stranded DNA antibody level |
glomerulonephritis |
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Availability | Mouse Genotype | ||||||||||||||||||
Rubcnem1Dgre/Rubcnem1Dgre | * |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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